To make a retrospective observation on the curative effect of the Chinese patent medicine Yangxinshi tablet in treating heart failure caused by dilated cardiomyopathy(DCM) after routine treatments.Methods： One hundred and twenty six patients suffering from heart failure caused by DCM were randomly divide into control group (n=62) and treatment group (n=64). The control group adopted routine therapy and patients in the treatment group were given further treatment of Yangxinshi tablet after treated with routine therapies. The usage and dosage were oral administration of 1.8g each time， three times a day. Three months later， the grading changes of NYHA cardiac function， left ventricular ejection fraction (LVEF) and NT-proBNP of the two groups were observed and compared. Results： The observation showed that the grading changes of NYHA cardiac function， LVEF and NT-proBNP of the two groups were improved (P<0.05 or P<0.01) after treatment. But the curative effect of treatment group was more apparent than that of the control group. There was statistical significance in comparison of the two groups （P<0.05）. Conclusion： Yangxinshi tablet has significant clinical curative effect in treating patients suffering from heart failure caused by dilated cardiomyopathy(DCM).