世界中医药

目的：回顾性观察在常规治疗基础上加用中成药养心氏片对扩张型心肌病(Dilated Cardiomyopathy，DCM)心力衰竭患者的治疗效果。方法：将126例DCM心力衰竭患者随机分为对照组62例和治疗组64例，对照组采用常规方法治疗，治疗组在此基础上加养心氏片治疗，用法用量为1.8 g/次，3次/d，口服；治疗3个月后观察两组NYHA心功能分级变化、左室射血分数（LVEF）以及N端脑利钠肽前体值（NT-proBNP）并加以对比。结果：观察显示两组NYHA心功能分级、LVEF及NT-proBNP均较治疗前有所好转（P<0.05或P<0.01），但治疗组疗效比对照组更为明显，两组比较有统计学意义（P<0.05）。结论：养心氏片对扩张型心肌病心力衰竭患者有显著临床疗效。

English Summary:

To make a retrospective observation on the curative effect of the Chinese patent medicine Yangxinshi tablet in treating heart failure caused by dilated cardiomyopathy(DCM) after routine treatments.Methods： One hundred and twenty six patients suffering from heart failure caused by DCM were randomly divide into control group (n=62) and treatment group (n=64). The control group adopted routine therapy and patients in the treatment group were given further treatment of Yangxinshi tablet after treated with routine therapies. The usage and dosage were oral administration of 1.8g each time， three times a day. Three months later， the grading changes of NYHA cardiac function， left ventricular ejection fraction (LVEF) and NT-proBNP of the two groups were observed and compared. Results： The observation showed that the grading changes of NYHA cardiac function， LVEF and NT-proBNP of the two groups were improved (P<0.05 or P<0.01) after treatment. But the curative effect of treatment group was more apparent than that of the control group. There was statistical significance in comparison of the two groups （P<0.05）. Conclusion： Yangxinshi tablet has significant clinical curative effect in treating patients suffering from heart failure caused by dilated cardiomyopathy(DCM).

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