世界中医药

目的：观察电针三阴交穴对自然更年期大鼠焦虑行为学的影响。方法：将大鼠分为正常组、模型组和治疗组，治疗组在三阴交穴处进行电针，隔日1次，共治疗15次。正常组、模型组常规饲养，隔日抓取刺激。记录在高架十字迷宫实验中焦虑行为数据（进入开放臂次数、向下探究次数、封闭臂后腿直立次数和进入开放臂时间等）。结果：与正常对照组比较，模型组的OE%、OT%均显著减少，差异有统计学意义（P<0.05，P<0.01），HD值均显著升高，差异有统计学意义（P<0.01）表现出明显的焦虑症状，模型组、治疗组的OE+CE差异均无统计学意义（P>0.05）；与模型组比较，治疗组的OE%及OT%均显著增高，差异有统计学意义（P<0.05），治疗组的HD值明显降低，差异有统计学意义（P<0.05）；RE值无统计学意义。结论：电针三阴交有一定的抗焦虑作用。

English Summary:

To observe the effect of electrical acupuncture in Sanyinjiao acupoint on anxiety-like behavior of natural climacterium rats. Methods：The rats were divided into normal control group， model group and treatment group. Rats in the treatment group were given electro-acupuncture at Sanyinjiao acu-point once every other day for15 sessions. Rats in the other two groups were fed with conventional methods， and received stimulation every other day. The data of anxiety behavior were recorded， including times of entering the open arm， times of rear leg upright standing in the closed arm， time entering the open arm， etc. Results： Compared with normal control group， the percentages of close-area time (OE%) and open-area time (OT%) showed an decreasing trend in model group， and the difference was significant (P<0.05， P<0.01) which showed significant symptoms of anxiety; but the difference of OE and CE between the model group and treatment group was not statistically significant (P>0.05); compared with model group， the percentages of OE and OT increased greatly， and the difference was statistically significant (P<0.05); the value of HD in model group increased greatly， and the difference was statistically significant (P<0.01)， the HD value in treatment group showed a downward trend， and the difference was significant (P<0.05)， but the RE value was not statistically significant. Conclusion： Electrical acupuncture in Sanyinjiao acupoint shows certain anti-anxiety effect.

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