| 引用本文:黄世敬 张永超 张 颖.黄芪治疗抑郁症应用与研究[J].世界中医药,2014,9(05):. |
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| 黄芪治疗抑郁症应用与研究 |
| Application and Research of Milkvetch Root in the Treatment of Depression |
| 投稿时间：2013-08-05 |
| DOI：10.3969/j.issn.1673-7202.2014.05.039 |
| 中文关键词: 黄芪 抑郁症 配伍应用 抗抑郁 |
| English Keywords:Milkvetch Root Depression Application Compatibility Anti-depression |
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| 中文摘要: |
| 目的：探讨黄芪在治疗抑郁症中的应用。方法：结合抑郁症病机特点，通过文献分析，总结其配伍应用规律。结果：黄芪在治疗抑郁症中有养心通血脉、益气开郁；益肺助宣肃、固表解郁；护肝利疏泄、和中解郁；健脾助运化、升阳解郁；益肾助气化、利水解郁之功，随证配伍，开郁行滞。其抗抑郁机制主要涉及下丘脑-垂体-肾上腺轴、免疫功能、细胞因子及神经细胞等的调节。结论：对其配伍应用及作用机制的深入研究，将为补气中药治疗抑郁症提供科学依据。 |
| English Summary: |
| To explore the application of milkvetch root in treatment of depression.Methods：In accordance with the pathogenesis of depression， the application rule of compatibility of medicine was summarized through literature analysis.Results：Milkvetch root could nourish the heart and promote blood circulation， tonify qi to alleviate mental depression， moisturize the lung to regulate up and down activity， strengthen the body surface resistance to resolve depression， protect the liver and promote dispersion and regulate the middle warmer to resolve depression， fortify the spleen and help transportation and transformation and raise yang to resolve depression， and tonify the kidney and help gasification and promote the circulation of water to resolve depression.Through the compatibility of medicine according to syndromes，it could resolve depression and move stagnation.The antidepressant mechanism mainly involved hypothalamic pituitary adrenal axis， inflammatory cytokines， immunologic function， nerve cells etc.Conclusion：In-depth study on its application and compatibility of medicine and mechanism will provide scientific basis for TCM clinical treatment of depression. |
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