世界中医药
文章摘要
引用本文:李景松 张贵君.甘草饮片、药对以及四君子汤中药效组分的测定[J].世界中医药,2014,9(06):.  
甘草饮片、药对以及四君子汤中药效组分的测定
Determination of Active Components Alignments from Licorice Single Herb,Pair Herb and Sijunzi Decoction
投稿时间:2013-12-08  
DOI:10.3969/j.issn.1673-7202.2014.06.033
中文关键词:  内蒙古野生甘草  质量评价指标  药效组分  四君子汤
English Keywords:Liquorice  Quality standard indicators  Active components alignments  Sijunzi decoction
基金项目:中药新产品开发与产业化及中药资源保护利用研究,课题名称:蚕砂药效组分中药研究(编号:桂科攻10124008-14)
作者单位
李景松 张贵君 北京中医药大学中药学院北京100102 
摘要点击次数: 1533
全文下载次数: 2020
中文摘要:
      目的:以内蒙古野生炙甘草单味药、药对、复方为研究载体,测定甘草中4种药效组分含量,探索药效组分变化规律。方法:采用单味药、药对配伍、复方配伍组分-液相色谱综合分析法。结果:药效组分甘草苷-甘草素-甘草酸-异甘草苷在单味药(内蒙古野生炙甘草)中含量为(12.14±0.31),(3.25±0.19),(38.75±1.77),(1.4±0.25);在药对(炙甘草-人参)中含量为(2.87±0.04),(0.74±0.02),(6.42±0.18),(0.37±0.03);在药对(炙甘草-白术)中含量为(5.99±0.01),(2.16±0.09),(22.4±1.8),(0.77±0.02):在复方(四君子汤)中含量为(2.99±0.03),(0.81±0.04),(10.05±0.31),(0.32±0.03)。结论:甘草中4中药效组分在单味药、药对、复方中含量存在一定差异,为进一步完善甘草药材质量的制定提供新思路和科学依据。
English Summary:
      To explore regularity of the active components alignments (ACA)through determination of the ACA in inner Mongolia wild licorice single herb,herb-herb and prescription. Methods: The ACA were determined by reversed phase high-performance liquid chromatography (RP-HPLC) in single herb,herb-herb and prescription. Results: The contents of liquiritin-liquiritigenin-glycyrrhizin acid-Isoliquiritin in single liquorice herb were(12.14±0.31),(3.25±0.19),(38.75±1.77),(l1.4±0.25; in herb-herb (honey-fried licorice-ginseng) were(2.87±0.04),(0.74±0.02),(6.42±0.18),(0.37±0.03); in herb-herb(honey-fried licorice - bighead atractylodes rhizome ) were (5.99±0.01),(2.16±0.09),(22.4±1.8),(0.77±0.02); in prescription were(2.99±0.03),(0.81±0.04),(10.05±0.31),(0.32±0.03). Conclusion: There are some differences in the content of liquiritin- liquiritigenin-glycyrrhizic acid-Isoliquiritinin in single herb,herb-herb and prescription,which provides scientific basis and a new way for the establishment of improving the quality of licorice.
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