To explore the clinical effects of Chinese medicine on precancerous lesions of gastric cancer(PLGC) according to syndrome differentiation. Methods： The patients with PLGC were divided into five syndrome differentiation groups according to their clinical symptoms， gastroscopy examinations and pathological biopsy， and they were given treatment accordingly for 3 months respectively. Results： After therapy， the total effective rate was 71.2%. Besides， the scores of gastric mucosal atrophy， dysplasia and intestinal metaplasia were improved significantly(P<0.05). Conclusion： Chinese medicine according to syndrome differentiation has the advantage of better clinical effect. It can reverse PLGC and reduce the incidence rate of gastric cancer. Its worthy to be widely spread in clinical condition.