世界中医药

目的：观察针刺治疗第三腰椎横突综合征的止痛作用，并探讨其镇痛机制。方法：对40例第三腰椎横突综合征患者进行针刺治疗(穴取横突处阿是穴、肾俞、委中，3次/周，3周为1个研究周期)；并于治疗前(第0周)、治疗后(第3周)、回访时(第5周)用视觉模拟评分法(Visual Analogue Scale，VAS)进行疼痛评分；并用酶联免疫吸附试验(Enzyme Linked Immunosorbent Assay，ELISA)法检测血清白细胞介素6(Interleukin-6，IL-6)、白细胞介素10(Interleukin-10，IL-10)的水平。结果：治疗后(第3周)时，VAS值下降(P<0.05)，血清IL-6、IL-10水平上升(P<0.05)；回访时(第5周)VAS值下降(P<0.05)，血清IL-6、IL-10水平下降(P<0.05)。结论：针刺对第三腰椎横突综合征有很好的止痛作用，其镇痛机制很可能是促进细胞因子的代谢进程。

English Summary:

To observe the analgesic efficacy of acupuncture treatment on the third lumbar trans-verse process syndrome， and to explore the analgesic mechanism. Methods： Forty patients with the third lumbar trans-verse process syndrome were given acupuncture therapy in acupoints of ashi(on transverse)， Shenshu( BL-23)， Weizhong(BL-40) with 3sessions a week， 3 weeks as a course. The pain (VAS) and the level of interleukin-6， interleukin-10 in the serum detected by ELISA after treatment (on the third week) and returned visit (on the fifth week) were recorded. Results： After 3 weeks of treatment， the score of VAS decreased (P<0.05)， and the level of interleukin-6 and interleukin-10 in the serum were increased (P<0.05). In the return visit， the value of VAS decreased (P<0.05)， and the level of interleukin-6， interleukin-10 in the serum were fallen (P<0.05). Conclusion： Acupuncture treatment on the third lumbar trans-verse process syndrome had a better analgesic effect， and its analgesic mechanism may be promoting the metabolism of cytokines.

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