To observe and compare the effects of emergency thrombolytic therapy combined with traditional Chinese medicine on the vascular recanalization and complications rates of the patients with acute myocardial infarction (AMI). Methods： One hundred and twenty cases of AMI patients were selected as the research objects and randomly divided into the observation group (n=60) and the control group (n=60). The patients in the control group were treated with intravenous infusion of urokinase thrombolysis therapy combined with oral administration of aspirin, while the patients in the observation group were treated with intravenous infusion of urokinase thrombolysis therapy combined with traditional Chinese medicine. The vascular recanalization rates, the bleeding complications rates, and the severe myocardial infarction complications rates of the patients in the two groups were observed and compared. Results： The vascular recanalization rates of the patients in the observation group and the control group were 73.3% and 50% respectively. The rate of the observation group was significantly higher than that of the control group (P<0.05); the rate of occluded vessels appearing at the 1st week after treatment of the control group was significantly higher than that of the observation group (P<0.05). The proportion of the patients with the bleeding complications of the observation group was significantly lower than that of the control group (P<0.05). The proportions of the patients with the severe myocardial infarction complications such as shock, heart failure, arrhythmia in the observation group were significantly lower than those of the control group (P<0.05). Conclusion： The application of emergency thrombolytic therapy combined with traditional Chinese medicine in treatment of the patients with AMI can improve the recanalization rates, reduce the rates of the bleeding complications and severe myocardial infarction complications and has a positive significance for improving the prognosis of patients.