世界中医药
文章摘要
引用本文:黄建东 韦安暄.健脾调肝汤治疗晚期原发性肝癌对生活质量的影响[J].世界中医药,2014,9(10):.  
健脾调肝汤治疗晚期原发性肝癌对生活质量的影响
Impact of Jianpi Tiaogan Tang on Life Quality of Patients with Terminal Primary Liver Cancer
投稿时间:2013-01-23  
DOI:10.3969/j.issn.1673-7202.2014.10.019
中文关键词:  晚期原发性肝癌/中西医结合疗法  健脾调肝汤  生活质量
English Keywords:Terminal primary liver cancer/ Integrated Chinese and western treatment  Jianpi Tiaogan Tang  Quality of life
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作者单位
黄建东 韦安暄 广西扶绥县中医院消化内科广西崇左532199 
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中文摘要:
      目的:观察健脾调肝汤治疗晚期原发性肝癌对生活质量的影响。方法:将60例患者随机分成治疗组与对照组各30例,2组患者均采用相同的西药(保肝、降酯、止痛等)治疗;治疗组同时加用健脾调肝汤治疗。2组均治疗1个月为1个疗程,2个疗程后评价疗效。观察2组中医证候变化、生活质量、体重变化、肝功能变化及不良反应。结果:2组中医临床证候变化比较,治疗组与对照组总改善率分别83.3%与60.0%(P<0.05);2组治疗后生活质量及体重变化比较,生活质量、体重治疗组高于对照组(P<0.05);2组治疗后肝功能变化比较,2组治疗后肝功能3项指标(ALT、AST、TBIL)较治疗前均有明显改善(P<0.05),其中ALT、AST水平治疗组较对照组改善更明显(P<0.05)。不良反应2组未见明显发生。结论:健脾调肝汤治疗晚期原发性肝癌可改善临床症状,减轻肝损害及不良反应,提高生活质量、延长生存期。
English Summary:
      To observe impact of Jianpi Tiaogan Tang on the life quality of patients with terminal primary liver cancer.Methods:Sixty patients were randomized to receive western medicine treatment (protecting liver, lipid lowering, pain relief, etc.), the treatment group took Jianpi Tiaogan Tang on top of western medicine treatment. After 2 treatment courses (1 month/course), efficacy were evaluated. TCM syndrome, life quality, weight changes, liver function changes and adverse reaction were observed.Results:In terms of TCM syndrome changes, the total improvement rate of treatment group and control group were 83.3% and 60.0% respectively (P<0.05); after treatment, the treatment group was significantly better than control group in terms of life quality, weight stabilization (P<0.05); in terms of liver function, after treatment both groups showed significantly improved ALT、AST、TBil (P<0.05). Treatment group had even better ALT, ASL levels compared to control group (P<0.05). No adverse reaction was observed in both groups.Conclusion:Jianpi Tiaogan Tang can alleviate clinical symptoms of terminal primary liver cancer, reducing liver damage and adverse reaction, improve quality of life and prolong lifetime.
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