To explore purification techniques of Resveratrol by macroporous adsorption resin. Methods:As resveratrol is acidic, lye elution resin separation and purification was used. The impact of resin types, NaOH concentration, flow rate on purification results were explored. Results:The optimized purification techniques was: NKA-Ⅱ resin, eluent concentration of NaOH 0.5%, flow rate=1BV/h, after desalting, resveratrol purity >=70%. Conclusion:The optimized purification techniques is applicable to adsorption resin that is resveratrol adsopting, separation with other ingredients can be achieved by one flow, it is suitable for mass production.