| 引用本文:赵进东 舒仪琼 吴吉萍 凌含鹏 谢峰涛 侍 磊 方朝晖.通心络胶囊对糖尿病性周围神经病变患者神经传导速度作用的系统评价[J].世界中医药,2014,9(10):. |
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| 通心络胶囊对糖尿病性周围神经病变患者神经传导速度作用的系统评价 |
| Systematical Review on Effect of Tongxinluo Capsule on Nerve Conduction Velocity of Patients with Diabetic Peripheral Neuropathy |
| 投稿时间：2014-09-15 |
| DOI：10.3969/j.issn.1673-7202.2014.10.039 |
| 中文关键词: 通心络胶囊 糖尿病性周围神经病变 有效性 系统评价 |
| English Keywords:Tongxinluo capsule Diabetic Peripheral Neuropathy Validity Meta-analysis |
| 基金项目:国家中医药管理局中医药重点学科（编号：20091221）；国家中医药管理局国家基本公共卫生服务项目（编号：20131012）；安徽省卫生厅中医药科研课题项目（编号：2012zy26） |
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| 中文摘要: |
| 目的：评价通心络胶囊对糖尿病性周围神经病变患者神经传导速度作用的有效性。方法：计算机检索Cochrane图书馆临床对照试验资料库、Pubmed Embase、中国生物医学文献数据库、中国期刊全文数据库、万方期刊数据库等相关资料，按照Cochrane系统评价的方法，客观评价纳入研究的质量，提取有效数据，采用RevMan 5.2软件进行Meta分析。结果：共纳入14个随机对照试验，包括1 078例患者。结果显示，与对照组相比，通心络胶囊能进一步提高正中神经及腓总神经的运动神经传导速度［SMD=-1.10，95% CI(-1.54，-0.65)，P<0.01］，［SMD=-1.83，95% CI(-2.35，-1.30)，P<0.01］；提高正中神经及腓总神经的感觉神经传导速度［SMD=-1.27，95% CI(-1.80，-0.75)，P<0.01］，［SMD=-1.60，95% CI(-2.39，-0.81)，P<0.01］。结论：通心络胶囊对糖尿病性周围神经病变患者神经传导速度作用是有效的。 |
| English Summary: |
| To evaluate efficacy of Tongxinluo capsule in improving the nerve conduction velocity of patients with diabetic peripheral neuropathy.Methods:Randomized controlled trials were electronically retrieved from Cochrane Library,Pubmed Embase,CBM,CNKI,Wanfang Database,and so on.All articles were assessed according to the Cochrane Handbook for Systematic Reviews of interventions and then effective data were analyzed by RevMan 5.2 soft ware.Results:Fourteen randomized controlled trials involving 1078 patients were included.Results of Meta-analysis showed that there was statistical difference in the motor nerve conduction velocity of median nerve and common peroneal nerve［SMD=-1.10，95% CI(-1.54，-0.65)，P<0.01］and［SMD=-1.83，95% CI(-2.35，-1.30)，P<0.01.the sensory nerve conduction velocity of Median nerve and common peroneal nerve were improved［SMD=-1.27，95% CI(-1.80，-0.75)，P<0.01］and［SMD=-1.60，95% CI(-2.39，-0.81)，P<0.01］.Conclusion:The treatment plan of Tongxinluo capsule for Diabetic Peripheral Neuropathy is efficacy. |
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