世界中医药

目的：社区应用不同疗法治疗糖尿病患者，评估应用脑心通胶囊针对预防糖尿病心脑血管意外、实验室指标及干预颈动脉内层中膜厚度的临床疗效。方法：67例糖尿病患者分为2组予延续西药降糖、降脂等治疗。中药组应用脑心通胶囊治疗，对照组不应用中药汤剂或中成药治疗。持续治疗1年后从心脑血管不良事件、颈动脉彩超结果及血糖、血脂、糖化血红蛋白等生化指标等方面，评估其治疗效果。结果：与治疗前相比，中药组与对照组血脂较治疗前差异有统计学意义（P<0.05），且2组间比较差异有统计学意义（P<0.05）。中药组在IMT、血糖、糖化血红蛋白等指标方面治疗前后比较差异有统计学意义（P<0.05），而对照组治疗前后比较差异无统计学意义（P>0.05），2组比较差异有统计学意义（P<0.05），中药组心脑血管不良事件较对照组少。结论：社区的糖尿病患者应用脑心通胶囊治疗有益于血糖、血脂控制，血管内皮保护及预防心脑血管不良事件。

English Summary:

Abstract Objective： To observe cardiovascular events，changes of laboratory parameters，and carotid internal media thickness in diabetic patients applied with different treatment regimens.Methods:Sixty-seven patients were divided into 2 groups，both groups were treated with western medicines，the Chinese medicine group was treated with Naoxintong in addition.After 1 years of continuous treatment，therapeutic effect was evaluated based on incidence of cardiovascular events，IMT， blood glucose and lipids，glycated hemoglobin and other biochemical indicators.Results:There were significant blood lipid differences after treatment in both treatment groups (P<0.05)，and the difference was significant between 2 groups (P<0.05).There was statistical significance before and after treatment in Chinese medicine group in IMT，blood glucose，glycosylated hemoglobin protein index (P<0.05)，while the control group before and after treatment had no significant difference (P>0.05)，there was significant difference between 2 groups (P<0.05).The Chinese medicine group had less cardiovascular event incidence compared with the control group.Conclusion:Naoxintong has good effect for treating blood glucose and blood lipids which helps to prevent incidence of cardiovascular events in diabetic patients.

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