To explore the curative effect of traditional Chinese medicine injection in the application of first-aid of shock.Methods:Forty six shock patients admitted in our hospital during May 2011 to March 2013 were randomly divided into treatment group (n=23) and control group (n= 23). Systematical analysis was made.Results:The significant efficiency rate in treatment groups was 78.26%, and its total effective rate was 90.69%; the control group had the significant efficiency rate of 60.86%, and its total effective rate was 88.37%. There was statistically significant difference between the two groups in terms of the effective rate (P<0.05). After treatment, systolic blood pressure of patients in both groups increased, and one hour after treatment, systolic blood pressure of patients in treatment group was higher than that of the control group, and the difference was statistically significant (P<0.05); as the time growing, 2 hours after treatment, the difference was further increased. Heart rates of patients in both groups decreased 30 min after taking the medication, and the average heart rate of the treatment group was lower than that of the control group, and the difference was statistically significant (P<0.05). The amount of urine was increased in both groups two hours after treatment, and the treatment group had more urine (P<0.05).Conclusion:TCM syndrome differentiation and prescriptions applied on patients with different types of shock can regain Yang and change inverse, deliver Yin solid, and arouse spirit, and it can also effectively improve the microcirculation in the pathological state. The organic combination of TCM and modern medical first aid measures can improve the cure rate and have more advantages compared with a single therapy. Importance shall be attached to clinical application of traditional Chinese medicine injection in pre-hospital first aid.