| 引用本文:南风艳.中西医结合治疗排卵功能障碍性不孕症临床分析[J].世界中医药,2015,10(01):. |
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| 中西医结合治疗排卵功能障碍性不孕症临床分析 |
| Clinical Analysis of Treatment of Ovulation Dysfunction Infertility with Integrated traditional Chinese and Western Medicine |
| 投稿时间：2014-03-16 |
| DOI：10.3969/j.issn.1673-7202.2015.01.016 |
| 中文关键词: 排卵功能障碍 不孕症 左归丸 右归丸 桃红四物汤 中西医结合疗法 |
| English Keywords:Ovulation dysfunction Infertility Zuogui Wan Yougui Wan Taohong Siwu Tang Therapy of integrated traditional Chinese and Western Medicine |
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| 中文摘要: |
| 目的:观察中西医结合疗法对排卵功能障碍性不孕症患者的临床疗效。方法:将符合标准的230例患者按随机数字表法分为观察组(118例)和对照组(112例)。对照组采用氯米芬治疗，观察组加用补肾活血中药治疗，偏肾阳虚者使用右归丸合桃红四物汤加减，偏肾阴虚者使用左归丸合桃红四物汤加减。观察患者治疗后激素水平(LH和E2)、基础体温、Insler评分、子宫内膜厚度、优势卵泡直径和成熟卵泡数变化情况，统计排卵率和妊娠率。结果:2组患者治疗后LH和E2水平均升高，组间比较，差异均有统计学意义(P<0.05)。2组患者治疗后基础体温恢复正常率分别为76.27%、64.29%，差异有统计学意义(P<0.05)。2组患者治疗后Insler评分、子宫内膜厚度、优势卵泡直径和成熟卵泡数比较，差异均有统计学意义(P<0.05)。观察组和对照组的总有效率(排卵率)分别为73.73%、55.36%，1年内成功妊娠率分别为67.80%、38.39%。组间比较，差异均有统计学意义(P<0.01)。结论:在氯米芬治疗的基础上加用中医辨证论治，使用补肾活血中药，有助于提高排卵功能障碍性不孕症的排卵率和妊娠率。 |
| English Summary: |
| To observe the clinical effect of integrated treatment of traditional Chinese and western medicine for anovulatory infertility. Methods: A total of 230 patients meeting the inclusion criteria were randomly divided into observation group (118 cases) and control group (112 cases). The control group was treated with clomiphene， the observation group were treated with kidney tonifying and blood activating Chinese medicines， in addition to clomiphene. The patients with kidney yang deficiency were given Yougui Wan and modified Taohong siwu Tang， the patients with kidney yin deficiency were given Zuogui pill and modified Taohong Siwu Tang. We observed the patients hormone levels (LH and E2)， basal body temperature， Insler score， endometrial thickness， diameter of dominant follicles and mature follicles calculation， the ovulation percentage and pregnancy percentage. Results: LH and E2 levels elevated in both groups after treatment， the differences between groups were statistically significant (P<0.05). The percentage of basal body temperature returning to normal were 76.27%， 64.29% respectively (P<0.05). Comparison of insler score， endometrial thickness， diameter of dominant follicles and mature follicles also showed significant difference (P<0.05). The observation group and the control group had an ovulation percentage 73.73%， 55.36% respectively， 1 year successful pregnancy were 67.80%， 38.39%， which was statistically significant (P<0.01). Conclusion: Combined treatment of clomiphene with TCM syndrome differentiated treatment-kidney tonifying and blood activating Chinese medicines-enhance cure of ovulation and pregnancy in patients with dysfunction infertility. |
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