Shanghan Lun is a great works on syndrome differentiation and treatment, incorporating theory, methods, prescriptions and medicines, linking theory with reality, and have extraordinary values in TCM history. Many classical prescriptions were used to treat cardiovascular and cerebrovascular diseases, and have good therapeutic effect. Guizhi Decoctionis is one of them. The use of Guizhi Decoction was summarized on the basis of research papers published in recent decades.