Insulin resistance is not only the pathogenesis basis of type Ⅱ diabetes， but also the etiological agent of hypertension， hyperlipidemia and coronary heart disease. Insulin resistance is associated with dysfunction of depots and palaces， especially the spleen， as well as liver and kidney. Research shows that more than 70 kinds of traditional Chinese medicines have hypoglycemic effect. Chinese herbal compounds and singal herbs effective for insulin resistance can promote blood circulation for removing blood stasis， nourish spleen and enrich qi， strengthen yin and clear heat， relieve liver and detoxication， resolve phlegm and dampness.