| 引用本文:孙雪松，许国磊.麻杏石甘汤加减治疗慢性阻塞性肺疾病急性发作临床观察[J].世界中医药,2015,10(02):. |
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| 麻杏石甘汤加减治疗慢性阻塞性肺疾病急性发作临床观察 |
| Clinical Observation on Modified Maxingshigan Decoction in Treating Acute Exacerbations of Chronic Obstructive Pulmonary Disease |
| 投稿时间：2014-04-26 |
| DOI：10.3969/j.issn.1673-7202.2015.02.012 |
| 中文关键词: 麻杏石甘汤 慢性阻塞性肺疾病急性发作 清热化痰 血管活性因子 炎性反应递质 |
| English Keywords:Maxingshigan Decoction Acute exacerbation of chronic obstructive pulmonary disease Clearing heat and resolving phlegm Vasoactive factors Inflammatory mediators |
| 基金项目:2009年中医药行业科研专项资助项目——中医药治疗流行性感冒高危人群轻症和重症的临床研究(编号：200907001-2A) |
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| 中文摘要: |
| 目的：观察麻杏石甘汤加减治疗慢性阻塞性肺疾病急性发作(AECOPD)的疗效。方法：将212例AECOPD患者按随机数字表法分为对照组和治疗组各106例，对照组给予西医常规治疗方案，治疗组在对照组基础上联合应用麻杏石甘汤加减治疗，1个疗程(14 d)后对比疗效及中医症候评分、肺通气功能等相关指标。结果：治疗组临床控制率40.57%优于对照组的24.53，治疗组治疗后咳嗽、痰量、喘息、气短等中医症候评分均低于对照组，FEV1%预计值、FEV1/FVC等肺通气功能指标治疗前后差值均高于对照组，差异均有统计学意义(P<0.05)。结论：麻杏石甘汤加减治疗AECOPD可清热化痰、解毒祛瘀，促进临床症状缓解，改善肺通气功能，提高疗效。 |
| English Summary: |
| To observe the effects of Maxing Shigan Decoction in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) effect.Methods：Two hundred and twelve patients with AECOPD were randomly divided into control group and observation group with 106 cases in each group,the control group was given conventional western medicine treatment,the observation group in the control group based on the combined application of Maxingshigan decoction,1 courses (14 d) related indicators contrast curative effect and TCM syndrome score,lung ventilation function.Results：The clinical control rate of the observation group was 40.57%,which was better than the 24.53% of the control group.The TCM symptom scores of cough,phlegm,wheezing and shortness of breath after treatment in observation group were lower than those of the control group.The FEV 1% value,FEV1/FVC expected around pulmonary ventilation function indexes of treatment difference was higher than that of control group,and the differences were statistically significant (P<0.05).Conclusion：Maxingshigan Decoction in the treatment of AECOPD can heat phlegm,detoxification and remove blood stasis,promote the clinical symptoms,improve lung function,and improve the curative effect. |
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