世界中医药
文章摘要
引用本文:王学妍1,李明哲1,王士彪2,刘晓晨1,高天舒2.中药治疗亚急性甲状腺炎疗效Meta分析[J].世界中医药,2015,10(02):.  
中药治疗亚急性甲状腺炎疗效Meta分析
Meta Analysis of Efficacy of Traditional Chinese Medicine in Subacute Thyroiditis Treating
投稿时间:2014-10-29  
DOI:10.3969/j.issn.1673-7202.2015.02.030
中文关键词:  亚急性甲状腺炎  疗效  中药  循证医学  Meta分析  随机对照试验  临床对照试验
English Keywords:Subacute thyroiditis  Clinical efficacy  Traditional Chinese medicine  Evidence-based medicine  Meta-analysis  Randomized controlled trial(RCT)  Controlled clinical trial(CCT)
基金项目:辽宁省医学高峰建设工程(编号:2010056)
作者单位
王学妍1,李明哲1,王士彪2,刘晓晨1,高天舒2 1 辽宁中医药大学附属第三医院沈阳110032 2 辽宁中医药大学附属医院沈阳110003 
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中文摘要:
      目的:评价中药治疗甲状腺功能亢进症的有效性及安全性。方法:计算机检索关于中药治疗甲亢的人体临床试验研究文献,选择从1980年1月至2014年1月符合要求的随机对照试验(RCT)和临床对照试验(CCT)的文章,并按排除原则进行筛选,利用Cochrane手册进行文献质量评价,利用RevMan 5.2软件进行Meta分析。结果:共纳入16篇随机对照试验,所有文献入组患者合计702例,有效661例,对照组合计590例,有效462例。Meta分析结果显示,中药治疗亚急性甲状腺炎与单纯西药治疗比较总有效率(治愈率+好转率)的差异有统计学意义[OR=0.22,95%CI(0.15,0.33),P<0.01]。结论:采用中药治疗亚急性甲状腺炎的总有效率和治愈率明显优于单纯使用西药。
English Summary:
      To evaluate the efficacy and safety of Traditional Chinese medicine treatment of hyperthyroidism. Methods:computer retrieval literature about clinical research of traditional Chinese medicine in the treatment of hyperthyroidism,selected RCT &CCT researches in human body comply with the requirements from the establishment to 2014 since January,Meta analysis was performed to assess the quality of literatures,by using RevMan 5.2 software(download from Corhrane collaboration network),using Cochrane manual to evaluate the articles. Results:in the 16 randomized controlled trials involving 702 patients were included,661 patients were effective,controlled group involving 590 patients were included,462 patients were effective. Meta analysis showed that the traditional Chinese medicine in the treatment of subacute thyroiditis and simple western medicine in the treatment of total effective rate(cure & better),the difference was statistically significant[OR=0.22,95%CI(0.15,0.33),Z=7.76,P< 0.01].Conclusion:the effective rate and cure rate is better than pure western medicine group using traditional Chinese medicine treatment of subacute thyroiditis.
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