| 引用本文:岳鹏飞，但济修，谢元彪，刘红宁，杨明.难溶性中药成分纳米晶体给药系统的研究进展与思考[J].世界中医药,2015,10(03):. |
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| 难溶性中药成分纳米晶体给药系统的研究进展与思考 |
| Research Progress and Thinking on Nano-suspensions Delivery System of Indissoluble Substance of Traditional Chinese Medicine |
| 投稿时间：2015-02-02 |
| DOI：10.3969/j.issn.1673-7202.2015.03.002 |
| 中文关键词: 纳米晶体混悬系统 固体化 再分散性 |
| English Keywords:Nano-suspensions drug delivery system Solidification Redispersibility |
| 基金项目:国家自然科学基金项目(编号：81102821) |
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| 摘要点击次数: 1343 |
| 全文下载次数: 1978 |
| 中文摘要: |
| 纳米晶体混悬给药系统为改善难溶性中药成分的溶解度和生物利用度提供了一种新的途径。研究具有再分散性能的固体化纳米晶体给药系统，是实现纳米晶体混悬系统稳定化的理想选择，然而，固体化再分散后是否仍呈纳米状态，能否保持良好的再分散性，仍然是亟待解决的关键科学问题。文章主要综述了纳米晶体给药系统固体化的及其再分散性能的研究进展，以期“抛砖引玉”，进一步促进中药纳米晶体给药系统制剂理论的完善与发展。 |
| English Summary: |
| Nano-suspensions drug delivery system is used as a novel approach to improve the solubility and bioavailability of indissoluble substance of Chinese medicine. Re-dispersible solid nanosuspension drug delivery system is an ideal choice to achieve stability. However, the questions remain whether after solidification, the particle is still at nano-meter scale, with satisfactory re-dispensability With the aim to optimize the theory and application of the nano-suspensions drug delivery system, this paper provided the latest research status quo and analysis of research strategy. |
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