By retrospective analysis of related biochemical measurements of patients with liver cirrhosis induced by hepatitis,their characteristics and clinical significance in different stage of Child-pugh,compensated or decompensated period were discussed.Methods: Total 87 patients with liver cirrhosis induced by hepatitis were collected with the according standard in a fixed period of time(from 1 to 6 month,2014).Patients’ liver function(ALB,GLB,BIL,CHE,ALP,ALT,GGT,TBA),cruor(PT,PTA),BPC and PLT etc.in different grade and different Child stage were analyzed by T-test or Analysis of Variance in order to observe their characteristics and trend respectively.Results:Compared to the patients with compensatory stage,the age,Child score,and values of TBIL,ALP,TBA,INR and PT of patients in decompensatory stage was significantly higher(P<0.01),in the other hand,the values of ALB,PLT and CHE in decompensatory stage are lower than in compensatory stage(P<0.01).However there are no statistical difference in the index of GLB,ALT,AST,AFP(P>0.05).In the three group patients of Child A,B,C,the values of ALB,PLT and CHE gradually decreased with the increase of child classification,but TBIL,ALP,TBA,INR and PT increased with the increase of child classification,and there were no statistical difference in the index of GLB,ALT,AST,GGT,AFP(P>0.05).Conclusion:In the serum of patients with liver cirrhosis induced by hepatitis,the detection index of ALB,TBIL,ALP,TBA,CHE,PT,INR,PLT were associated with the severity of disease,which can be used to evaluate liver function and analyze disease prognosis.But the index of liver inflammation such as GLB,ALT,AST and changes of AFP were not accordance with the severity of liver cirrhosis.