To observe the effect of Yiqi Huoxue Recipe (YQHX) in treatment of elderly patients with Qi deficiency and blood stasis type 2 diabetic cerebral infarction (DCI).To investigate the role and mechanism of YQHX and its effects on blood glucose and lipid.Methods:Sixty-five cases of DCI were randomly divided into two groups. Apart from western medicine therapy, the 33 patients in observation group were treated with YQHX orally, and 32 cases in the control group were given intravenous drip of Sanqi Panax Notoginseng Injection. After 30 days of therapy, the clinical curative effect, the degree of neural function defect, blood glucose and blood lipid of the two groups before and after treatment were observed, and comparison was made.Results:The total clinical efficacy rate of observation group was 97% (32/33), which was significantly better than the control group (P<0.05). YQHX could improve the neurologic impairment degree, control blood glucose, reduce blood fat, improve the blood rheology. And the effect was better than that of the control group.Conclusion:Yiqihuoxue treatment of DCI could effectively lower hypoglycemic lipid, improve cerebral circulation, reduce the plasma endothelin and blood viscosity, protect vascular endothelial cells, enhance brain cells to hypoxia tolerance, and promote the recovery of neural function.