| 引用本文:钱春美，张晓峰.抗氧化作用样中药单体抑制Ox-LDL生成保护血管内皮细胞作用的研究进展[J].世界中医药,2015,10(04):. |
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| 抗氧化作用样中药单体抑制Ox-LDL生成保护血管内皮细胞作用的研究进展 |
| Investigation Progress in Chinese Medicine Monomer with Antioxidant Effect Inhibiting Ox-LDL Ggeneration and Protecting Vascular Endothelial Cells |
| 投稿时间：2014-09-23 |
| DOI：10.3969/j.issn.1673-7202.2015.04.040 |
| 中文关键词: 中药单体 氧化低密度脂蛋白 血管内皮细胞 动脉粥样硬化 |
| English Keywords:Chinese medicine monomer Ox-LDL Vascular endothelial cell AS |
| 基金项目:上海市卫生局科研项目（编号：20114057） |
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| 中文摘要: |
| 氧化低密度脂蛋白（Oxidized Low Density Lipoprotein，Ox-LDL）的形成对动脉粥样硬化（Atherosclerosis，AS）的发生发展起到很关键的作用，主要通过刺激相关受体、分泌细胞因子等诱导内皮细胞损伤，加重AS。近年来国内外对中药单体抗低密度脂蛋白氧化，减少对血管内皮细胞损伤，起到预防治疗动脉粥样硬化，保护心血管作用有很多报道。本文就近年来的中药单体抗Ox-LDL，保护心血管疾病的相关研究进行综述。 |
| English Summary: |
| Oxidized low-density lipoprotein (Ox-LDL) plays an important role in the formation of atherosclerosis (AS). It induces endothelial cell injury and aggravates AS by stimulating the relevant receptors, secreting cytokine and so on. In recent years, there are more and more reports about the antioxidant effect of Chinese medicine monomer in preventing and treating AS by reducing endothelial cell injury. This paper gives a summary review of some researches on the relationship between Ox-LDL and cardiovascular disease in recent years. |
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