| 引用本文:辛大永，符竣杰.二甲消癥汤治疗气虚血瘀型特发性肺间质纤维化临床观察[J].世界中医药,2015,10(05):. |
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| 二甲消癥汤治疗气虚血瘀型特发性肺间质纤维化临床观察 |
| Clinical Observation of Erjia Xiaozheng Decoction in Treating Idiopathic Pulmonary Fibrosis with Qi deficiency and Blood Stasis Syndrome |
| 投稿时间：2015-03-23 |
| DOI：10.3969/j.issn.1673-7202.2015.05.023 |
| 中文关键词: 特发性肺间质纤维化 二甲消癥汤 中医药治疗 临床观察 |
| English Keywords:IPF Erjia Xiaozheng decoction TCM treatment Clinical trial |
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| 中文摘要: |
| 观察二甲消癥汤治疗气虚血瘀型特发性肺间质纤维化患者的临床疗效。方法：将符合纳入标准的患者，抽取54例，随机分为对照组（26例）及治疗组（28例），对照组26例在维持治疗的基础上予以金水宝胶囊，每次3粒，3次/d；治疗组28例在维持治疗的基础上，合二甲消癥汤治疗；治疗1个疗程（3个月）后，进行疗效比较。结果：治疗组治疗后的中医症状积分、肺一氧化碳弥散量、6分钟步行距离较对照组有所改善（P<0.05）；但在肺总量、用力肺活量指标改善上2组无统计学意义。结论：二甲消癥汤对气虚血瘀型特发性肺间质纤维化的临床症状有较好的改善作用，能提高患者肺弥散功能，有效改善患者活动耐力。 |
| English Summary: |
| To observe the clinical efficacy of Erjia Xiaozheng decoction in the treatment of Idiopathic pulmonary fibrosis with qi deficiency and blood stasis syndrome. Methods: Fifty-four subjects with IPF were randomly divided into 2 groups according to treatment sequence: 26 subjects in control group were treated with Jinshuibao capsule, 4 capsules once, 3 times a day; 28 subjects in treatment group were treated with Jinshuibao capsule and Erjia Xiaozheng decoction.The therapeutic course was 6 weeks. Results: The symptom integral, diffusion capacity for carbon monoxide of the lung(DLCO), six-minute walking distance were improved more significantly in treatment group than in control group(P<0. 05).But there was no significant difference between the two groups in TLC and FVC. Conclusion: Erjia Xiaozheng decoction is effective for IPF with Qi deficiency and Blood stasis syndrome. The decoction may improve lung diffusing function and activity endurance. |
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