Abstract:To evaluate the risk factors that effect patients with chronic obstructive pulmonary disease (COPD) in Kizilsu Kirghiz Autonomous Prefecture of Xinjiang province, applying Analytic Hierarchy Process (AHP). Methods: The information of 318 patients with COPD from the hospitals of Kizilsu Kirghiz Autonomous Prefecture of Xinjiang province were collected by questionnaire survey, including the normal information, daily life factor, living environment factor, causes of disease, triggers and clinical symptoms. The math model was established by applying AHP method. Results: There were significant differences in factors of daily life pattern, living environment, personal differences, and disease history among the mild, moderate, severe patients (P<0.01). From the comparison of the first grade assessment indicator of the risk factor weight coefficient, the highest weight coefficient were personal factor (0.470) and factor of disease history (0.280), and factor of daily life (0.136) and factor of living environment (0.114) followed. In the second grade assessment indicator of the risk factors showed as follows: personal factors: the degree of smoking (0.231) > occupational dust exposure (0.475) > the degree of fatness (0.225) > economic situation (0.069); factors referring to daily life: the fuel cleanliness (0.349) > the kitchen ventilation (0.294) > the cleanliness of heating (0.266) > the cleanliness of food cooking (0.091); factors related to living environment: the living air quality (0.348) = the living surroundings (0.348) > the living ventilation rate (0.207) > degree of house lighting (0.097); factors referring to family history disease: the consolidation degree of disease (0.459) > the past medical history (0.325) > the degree of seasonal onset (0.149) > the degree of family history disease (0.067). Conclusion: It can decrease the onset of COPD by reducing smoking and occupational dust exposure and increasing the life environment as well as life quality.