From very beginning,traditional Chinese medicine emphasizes on the idea of correspondence between man and universe as well as the thought of oneness of man and nature as it’s kingly way.It was considered that Vigour is vital to human physiological function,which is the most essential and important Qi and is the primary motive force of life,presented by theory of primordial Qi based on yin and yang while yin affiliated to yang.According to the physics and pathology of Diabetes mellitus(DM),insufficiency of primordial QI is seen as the etiological factor and pathogenesis of diabetes.It is held that abnormality of ascending and descending which accompanied by essential substances of food is an obvious pathogenesis of DM that result from qi-movement disturbance and qi-blood imbalance,and regulation of its ascending and descending based on vigor is the basic therapeutic principle and strategically situated measurement.