| 引用本文:范宗静，吴旸，谢连娣，崔杰.从保护线粒体角度谈心肌缺血再灌注损伤[J].世界中医药,2015,10(07):. |
|
| 从保护线粒体角度谈心肌缺血再灌注损伤 |
| Study on Myocardial Ischemia Reperfusion Injury from the Perspective of Mitochondria Protection |
| 投稿时间：2014-07-07 |
| DOI：10.3969/j.issn.1673-7202.2015.07.041 |
| 中文关键词: 中药 心肌缺血再灌注损伤 线粒体 |
| English Keywords:Traditional Chinese Medicine Myocardial ischemia reperfusion injury Mitochondria |
| 基金项目:国家自然科学基金面上项目(编号:81273692)——“黄芪多糖对缺血再灌注人心脏微血管内皮细胞凋亡及信号转导通路的影响”;国家自然科学基金青年基金项目(编号:81102573)——“黄芪多糖对缺血再灌注损伤大鼠心肌线粒体mPTP开放及其调控因素的影响” |
|
| 摘要点击次数: 1430 |
| 全文下载次数: 1703 |
| 中文摘要: |
| 近年研究表明,线粒体在心肌缺血再灌注损伤的多个环节发挥作用,其主要作用机制与活性氧、细胞凋亡、膜通透性转换孔开放等方面有关,以线粒体为靶点中药的研究近几年来备受关注,文章从保护线粒体角度出发,对中药防治心肌缺血再灌注损伤的作用机制进行综述。 |
| English Summary: |
| In recent years, studies have shown that mitochondria plays a role in several stages of myocardial ischemia reperfusion injury. Its main mechanism involves reactive oxygen, cell apoptosis and mitochondrial permeability transition pore opening. Traditional Chinese medicine researches using mitochondria as target point have been given a lot of attention to in recent years. The article summarizes the mechanism of traditional Chinese medicine prevention of myocardial ischemia-reperfusion injury from the perspective of protecting mitochondria. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
