| 引用本文:陈茜，叶婷，冯程程，马丽.中药封包治疗糖尿病周围神经病变随机对照研究[J].世界中医药,2015,10(09):. |
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| 中药封包治疗糖尿病周围神经病变随机对照研究 |
| RCT of Diabetic Peripheral Neuropathy Treatment with Chinese Herbal Medicine Packets |
| 投稿时间：2015-05-08 |
| DOI：10.3969/j.issn.1673-7202.2015.09.011 |
| 中文关键词: 糖尿病周围神经病变 展筋通络中药 甲钴胺 中药封包 中西医结合疗法 |
| English Keywords:Diabetic peripheral neuropathy Relaxing sinew and activating col lateral herbal medicine Mecobalamin Medicine packets Chinese medicine combined with western medicine therapy |
| 基金项目:新疆维吾尔自治区自然科学基金项目(编号：2012211A096) |
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| 中文摘要: |
| 目的：观察展筋通络中药联合甲钴胺治疗糖尿病周围神经病变(Diabetic Peripheral Neuropathy，DPN)患者的疗效。方法：76例患者随机分为2组各38例，2组均在血糖控制稳定后开始观察;2组给予甲钴胺注射液，治疗组在此基础上给予展筋通络中药封包外敷治疗;观察2组治疗前后症状积分、运动神经传导速度(Motor Nerve Conduction Velocity，MNCV)及感觉神经传导速度(Sensory Nerve Conduction Velocity，SNCV)等指标的变化，疗程均为2周。结果：治疗组总有效率明显高于对照组(P<0.05);治疗组治疗后MNCV和SNCV显著改善(P<0.05)，且优于对照组(P<0.05，P<0.01);治疗后治疗组症状积分明显低于对照组(P<0.01)。结论：展筋通络中药封包热敷联合甲钴胺肌肉注射治疗糖尿病周围神经病变，能显著提高患者MNCV和SNCV，有效改善临床症状，且见效快、疗效确切。 |
| English Summary: |
| To observe the efficacy of mecobalamin injection combined with the relaxing sinew and activating col lateral herbal medicine in the treatment of diabetic peripheral neuropathy (DPN). Methods： We divided 76 patients randomly into two groups (38 patients in each group) and observed their stable glycemic after it was under control; two groups were both given mecobalamin injection while the treatment group was also given relaxing sinew and activating col lateral herbal medicine package topical treatment. The changes in symptom scores before and after treatment， motor nerve conduction velocity (MNCV) and sensory nerve conduction velocity (SNCV) and other indicators of a course of two weeks were observed. Results： The total effective rate of the treatment group was significantly higher than the control group(P<0.05). After treatment MNCV and SNCV of the treatment group significantly improved(P<0.05)， better than the control group (P<0.05， P<0.01); the integral of clinical symptom was less in treatment group than control group(P<0.01). Conclusion： The relaxing sinew and activating col lateral herbal medicine combined heat packets mecobalamin intramuscular treatment can significantly improve patient’s MNCV and SNCV and relieve the clinical symptoms， which is quick and effective. |
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