世界中医药

目的：探讨高血压前期人群中医体质与动脉硬化程度的改变的相关性。方法：收集高血压前期、高血压、正常血压者各300例为研究对象，对研究对象进行中医体质测评和动脉硬化检测，观察不同体质类型高血压前期人群的动脉硬化程度的改变。结果：双侧肱踝脉搏波传导速度(Brachial Ankle Pulse Wave Velocity，BaPWV)与踝臂指数(Ankle Brachial Index，ABI)呈上升趋势，高血压前期组比正常血压组高(P<0.05)，与高血压组的差异无统计学意义(P>0.05)。3组的动脉硬度相比较，差异有统计学意义(P=0.000)。动脉轻度硬化及动脉硬化的比例呈上升趋势。阴虚质、痰湿质及瘀血质为高血压前期人群动脉硬化的危险因素。结论：高血压前期患者BaPWV明显升高，提示有早期动脉硬度改变;高血压前期患者的动脉硬化程度与阴虚质、痰湿质及瘀血质相关。

English Summary:

To explore the correlation between the constitutional types in Traditional Chinese Medicine (TCM) and the degree of arteriosclerosis of the people with prehypertension. Methods： We tested 300 patients with prehypertention， hypertention and normotension respectively to figure out their TCM constitutional types and the degree of arteriosclerosis in order to observe how arteriosclerosis degree changes along with different TCM constitutional types. Results： It is found that there was an upward trend in the brachial ankle pulse wave velocity (BaPWV) and the ankle brachial index (ABI). Prehypertention group was higher than the normotension group (P<0.05); there was no difference between prehypertention group and hypertention group (P>0.05). The difference of arterial stiffness among three groups was statistically significant(P=0.000) And there is an upward trend in the degree of arteriosclerosis. Yin deficiency constitution， phlegm dampness constitution and static blood constitution are the risk factors which cause the arteriosclerosis in prehypertensive patients. Conclusion： It indicates an early change of arterial stiffness of prehypertensive patients when BaPWV increases obviously. The degree of arteriosclerosis is related to yin deficiency constitution， phlegm-dampness constitution and static blood constitution.

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