In recent years, the frequency of influenza has become a major public health problem affecting the health of residents, therefore, the influenza surveillance and early warning are particularly significant. Influenza surveillance has been the first infectious disease to have a global surveillance, global influenza surveillance has a more than 60 years history. This paper reviewed domestic and international influenza warning system briefly, and clarified the research status of influenza warning system, the establishment of influenza warning system with Chinese characteristics, and drew the conclusion that the establishment of influenza warning system should fully reflect the Chinese characteristics, and can learn from various methods and improve the characteristics of Chinese medicine to improve the treatment effect so as to reduce mortality rate.