| 引用本文:赵京霞1,2,3，郭玉红1,3，刘卫红1,2,3，刘清泉1,2,3.炎症复合体与流感病毒感染[J].世界中医药,2015,10(10):. |
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| 炎症复合体与流感病毒感染 |
| Inflammasome and Influenza Virus Infection |
| 投稿时间：2015-10-08 |
| DOI：10.3969/j.issn.1673-7202.2015.10.004 |
| 中文关键词: 炎症复合体 流感 |
| English Keywords:Inflammasome Influenza virus infections |
| 基金项目:北京市科委绿色通道专项项目(编号：Z141100006014056) |
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| 中文摘要: |
| 炎症复合体可识别和感受多种微生物产物及细胞内自身代谢性应激而活化胱天蛋白酶，诱导白介素-1β、白介素-18、白介素-33等促炎性反应细胞因子的分泌及多种炎症递质的释放，在抗流感病毒感染过程中发挥着重要作用。这可能为调控流感病毒介导的免疫反应提供新的作用靶点。 |
| English Summary: |
| Inflammasome is activated by a diversity of pathogens and endogenous danger signals，which results in Caspase-1 activation and secretion of pro-inflammatory cytokines such as IL-1β，IL-18 and IL-33.The activation of inflammasome has being recognized as a key player and potential therapeutic target in fighting influenza virus infections. |
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