世界中医药

目的：观察半夏泻心汤联合埃索美拉唑治疗慢性萎缩性胃炎的临床疗效。方法：选择2012年1月至2014年6月我院收治的慢性萎缩性胃炎患者100例，随机分为治疗组和对照组，各50例。对照组给予埃索美拉唑治疗；治疗组予半夏泻心汤联合埃索美拉唑治疗，2组均在治疗3个月后进行临床疗效观察比较。结果：治疗前2组胃黏膜萎缩和肠化积分差异无统计学意义（P>0.05）。治疗后2组的胃黏膜萎缩和肠化积分均低于治疗前（P<0.05）；治疗后治疗组的胃黏膜萎缩和肠化积分均低于对照组（P<0.05）。治疗后治疗组的总有效率为94.11%，对照组为66.05%，治疗组的有效率优于对照组(P<0.05)。结论：半夏泻心汤联合埃索美拉唑治疗慢性萎缩性胃炎的临床疗效好，临床观察无不良反应发生，值得临床推广。

English Summary:

To observe the clinical effects of Heart-Draining Decoction combined with esomeprazole in the treatment of chronic atrophic gastritis. Methods: We selected 100 patients who received treatment for chronic atrophic gastritis in our hospital from January 2012 to June 2014, and randomly divided them into treatment group and control group, 50 cases for each group. The control group was given esomeprazole and the treatment group received treatment of Heart-Draining Decoction combined with esomeprazole. Two groups were observed and compared for the clinical effects after 3 months of treatment. Results: There was no significant difference in the gastric mucosal atrophy and the intestinal metaplasia scores between the two groups before the treatment (P>0.05). After receiving treatment, the gastric atrophy and the intestinal integral scores of the two groups were lower than before (P<0.05). The atrophy and the intestinal integral of the treatment group were lower than those of the control group (P<0.05).The total effective rate of the treatment group was 94.11% and it was better than the control group whose effective rate was 66.05% (P<0.05). Conclusion: Heart-Draining Decoction combined with esomeprazole has a good clinical effect on treating chronic atrophic gastritis and there were no adverse reactions observed, therefore, it is worth a wide clinical application.

查看全文查看/发表评论下载PDF阅读器