Abstract:To study the clinical efficacy and the effect on the level of insulin-like growth factors-1(IGF-1) of using dredging governer meridian and regulating Shen in the treatment of vascular dementia. Methods: A total of 72 patients with vascular dementia were randomly divided into treatment group(36 patients), which used acupuncture as the therapy, and control group(36 patients), which was given oxiracetam. To evaluate Traditional Chinese Medicine(TCM) core symptoms scales, MoCA scales, NPI scales, MMSE scales, Hachinski scales, ADL scales and measured insulin-like growth factor-1 (IGF-1) levels before treatment and after 35 days of the treatment respectively. Results: The effective rate of TCM core symptoms scales in the acupuncture treatment group was significantly higher than the control group, and the difference was statistically significant (P<0.05). After the 35 days of treatment, the scores of each scale in the treatment group are higher than that of the control group(P<0.05). IGF-1 levels were significantly increased after treatment, and that in the acupuncture group was significantly higher than that of the drug control group, and the difference was statistically significant(P<0.05). Conclusion: Dredging governor meridian and regulating Shen acupuncture method can effectively improve the patients activities of daily living, cognitive function, manifestation, and improve the IGF-1 levels of patients with vascular dementia, which has a good effect on vascular cognitive impairment patients.