| 引用本文:梁永妍，陈少欢，云宝.调补肺肾法对慢阻肺稳定期综合预后指标影响的临床研究[J].世界中医药,2015,10(11):. |
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| 调补肺肾法对慢阻肺稳定期综合预后指标影响的临床研究 |
| Clinical Study on the Effect Regulating and Tonifying Lung and Kidney Method on Comprehensive Prognostic Indicators of COPD in Stable Phase |
| 投稿时间：2015-07-13 |
| DOI：10.3969/j.issn.1673-7202.2015.11.019 |
| 中文关键词: 调补肺肾法 慢性阻塞性肺疾病 稳定期 预后 |
| English Keywords:Regulating and tonifying lung and kidney method COPD Stable phase Prognosis |
| 基金项目:佛山市卫生局医学科研课题(编号:201487723) |
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| 中文摘要: |
| 目的:探讨调补肺肾法治疗慢性阻塞性肺疾病(COPD)稳定期的临床疗效,评价治疗COPD稳定期患者的预后作用。方法:选取2014年1月至2015年6月在我院就诊的COPD稳定期患者84例,采用随机方法将患者分为治疗组(42例)和对照组(42例),治疗组给予常规治疗和口服调补肺肾方药,而对照组仅给予常规治疗,观察2组临床疗效及综合预后情况。结果:2组治疗后中医症候总积分较治疗前均有所下降,而治疗组较对照组下降幅度明显(P<0.05);治疗组治疗总有效率为92.86%,明显高于对照组的64.29%,治疗组疗效优于对照组(P<0.05);2组治疗后肺功能均有所改善,其中治疗组FEV1和FEV1/预计值(%)、FVC和FVC/预计值(%)等指标改善情况优于对照组(P<0.05);治疗组治疗后呼吸困难情况、6 min行走距离和BODE评价总分均较治疗前有改善(P<0.05),而对照组治疗后6 min行走距离和BODE评价总分亦较治疗前有所改善(P<0.05),但呼吸困难情况改善不明显(P>0.05),治疗组治疗后呼吸困难情况、6 min行走距离和BODE评价总分均较对照组治疗后明显改善(P<0.05)。治疗组治疗后各免疫指标、生活质量指标和急性发作次数较对照组均有所改善(P<0.05)。结论：调补肺肾法能有效治疗COPD稳定期患者,改善患者预后情况。 |
| English Summary: |
| To observe the clinical effect of regulating and tonifying lung and kidney method on comprehensive prognostic indicators of Chronic Obstructive Pulmonary Disease(COPD) in stable phase. Methods: To select 84 patients with stable COPD in our hospital during 2012 August to 2014 April and randomly divided them into observation group (42 cases) and control group (42 cases). The observation group was given conventional therapy and orally taken regulating and tonifying lung and kidney prescription, while the control group was only given conventional treatment. Then to observe the clinical efficacy and prognosis of the two groups. Results: After treatment, TCM syndrome total score were decreased in both groups, while the observation group was more obvious(P<0.05); Total effective rate of the observation group was 92.86%, significantly higher than than 64.29% in the control group(P<0.05); After treatment, lung function indexes of the two groups were improved, while the indexes of FEV1/ the expected value (%), FVC and FVC/ predicted value (%) and other indicators in the observation groups performed better than the control group (P<0.05); After treatment, the observation group performed better in FEV1/ expected value, respiratory difficulties, 6min walking distance and BODE evaluation score than before (P<0.05). In comparison, after treatment, FEV1/ the expected value, 6min walking distance and BODE evaluation scores in the control group also improved than before(P<0.05), but no obvious improvement in respiratory difficulties were observed(P>0.05); After treatment, FEV1/ the expected value, difficulty in breathing, walking distance of 6min and BODE evaluation total score in the observation group were all better than those in the control group(P<0.05); After treatment the immune indexes, indicators of the quality of life and frequency of acute attack in the observation group was improved in a larger degree than those of the control group(P<0.05). Conclusion: Regulating and tonifying lung and kidney method is effective in the treatment of COPD patients in stable stage, and can improve the prognosis of the patients. |
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