D-galactose induced Alzheimers disease(AD)model has been widely acknowledged as the aging model both at home and abroad. Previous doctors have recognized that the deficiency of brain marrow caused by kidney deficiency as well as phlegm turbidity and blood stasis are the main pathogenesis of dementia. Based on the study of dementia in old age including AD, it is recognized that D-galactose induced Alzheimers disease model is somewhat coincided with the type of deficiency of brain marrow due to kidney deficiency, which was further discussed in this paper under the perspective of behavior, morphology and histopathology etc.