| 引用本文:夏芸芸1，苏晓琳2，姜巍3.中药治疗骨髓增生异常综合征临床疗效Meta分析[J].世界中医药,2016,(02):. |
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| 中药治疗骨髓增生异常综合征临床疗效Meta分析 |
| Clinical Effect of TCM for Myelodysplastic Syndromes (MDS)：A Meta-Analysis |
| 投稿时间：2015-04-23 |
| DOI：10.3969/j.issn.1673-7202.2016.02.045 |
| 中文关键词: 中药 骨髓增生异常综合征 Meta分析 |
| English Keywords:Traditional Chinese Medicines (TCM) Myelodysplastic Syndromes (MDS) Meta-analysis |
| 基金项目:国家中医药管理局“十二五”中医药重点学科中医血液病学建设项目 |
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| 中文摘要: |
| 目的：评价使用单纯中药或联合西药与单纯西药治疗骨髓增生异常综合征（MDS）临床疗效的差异。方法：检索1978年至2015年国内发表的中药治疗MDS的相关文献，收集比较单纯中药或联合西药与单纯西药治疗MDS的随机对照试验，采用Jadad质量评分表进行质量评价，采用Review Manager 5.1统计分析(由国际Cochrane协作网提供)。结果：采用单纯中药或联合西药组治MDS的总有效率明显优于单纯西药对照组，其差异有统计学意义［OR=3.39，95%CI（2.52,4.54），P<0.000 01］。结论：与单纯西药相比，中药治疗MDS疗效更确切，但由于纳入研究的质量较低，尚需更多高质量研究来进一步证实。 |
| English Summary: |
| To analyze and evaluate the differences of effects of traditional Chinese medicines (TCM), western medicines and TCM combining with western medicines in treatment of myelodysplastic syndromes (MDS). Methods: We searched articles, which were related to MDS treating with TCM published from 1978 to 2015, and collected papers of randomized controlled trials comparing effects of TCM, western medicine and TCM combining with western medicine on treating MDS. The quality of the included articles were assessed under the standard for evaluation of Jadad and made statistical analysis through Review Manager 5.1 provided by the Cochrane Collaboration. Results: There was significant difference between the experimental group which was applied TCM only or a combination of western medicines and the control group, applied western medicines only ［OR=3.39，95%CI（2.52,4.54），P<0.000 01］. Conclusion: Compared with western medicines, TCM is obviously effective in treatment of MDS. While the articles included in this study are relatively low quality, more high-quality researches are required to verify this conclusion. |
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