To observe the clinical value of velocity vector imaging(VVI) on selective PCI of peri-procedure myocardial injury(PMI). Methods: A total of 76 unstable angina patients who had successfully received treatment of PCI and belonged to Qi deficiency and blood stasis syndrome were concluded in the study. The patients were divided into a group of patients suffering from PMI (n=16) and a normal group of patients without PMI (n=60). All patients received the examination of traditional Echocardiography and VVI at pre-PCI and 24 h post-PCI to evaluate the level of ventricular wall motion, cardiac structural and left ventricular systolic function. Results: In comparison of systolic strain, the levels of patients suffering from PMI had a significant decline from pre-PCI to 24 h post-PCI in the region of myocardial infarction(P<0.05), but there were no significant changes in normal group. In comparison of systolic strain rate, the levels of patients suffering from PMI had a significant decline from pre-PCI to 24 h post-PCI in the region of myocardial infarction(P<0.05), but there were no significant changes in normal group. In terms of traditional Echocardiography, none of the group had a significant change in related parameters from pre-PCI to 24 h post-PCI. Conclusion: VVI may have a contribution to early detection of PMI, but more studies are needed to verify it.