世界中医药
文章摘要
引用本文:刘丽娟,海丽娜,张金玲,王瑞峰,雷娜,沈燕,秦文杰.基于文献与专利探讨中医治疗胃溃疡的用药规律[J].世界中医药,2016,(03):.  
基于文献与专利探讨中医治疗胃溃疡的用药规律
Literature Review of TCM Medication Rules on Treating Gastric Ulcer
投稿时间:2015-05-06  
DOI:10.3969/j.issn.1673-7202.2016.03.046
中文关键词:  胃溃疡  中医药  性味  归经  文献  专利
English Keywords:Gastric ulcer  Traditional Chinese Medicine  Nature and flavor  Meridian entry  Literature  Patents
基金项目:公益性行业科研专项经费项目(编号:201507002);科学技术部国家“十一五”支撑计划课题(编号:2011BAI07B03)
作者单位
刘丽娟,海丽娜,张金玲,王瑞峰,雷娜,沈燕,秦文杰 北京振东光明药物研究院有限公司北京100120 
摘要点击次数: 1367
全文下载次数: 1414
中文摘要:
      目的:研究中医治疗胃溃疡常用药物性味和归经的规律与特点,为胃溃疡的中医临床治疗提供借鉴。方法:1)借鉴循证医学和流行病学的思路与方法,系统检索中国学术期刊全文数据库相关文献220篇,将符合纳入标准的107篇胃溃疡的中医治疗文献中的药物归类,并分别查出其性、味、归经,进行统计分析;2)利用东方灵盾(WTM)数据库,对2324个胃溃疡相关专利主题词进行统计分析。结果:1)对文献所涉及中药的用药规律进行统计,发现肿瘤发热用药频次最高的前10味中药分别为:白及、甘草、三七、海螵鞘、黄芪、白芍、黄连、延胡索、白术、生姜(干姜、姜炭);主要是补益药、清热药、理气药与理血药;性多温、寒,味则以苦味为先,其次为甘、辛;“归经”以归脾经的药物为最,其次是胃、肝、肺经的药物;2)对WTM数据库命中专利进行统计,前10味药分别为:甘草、延胡索、白及、海螵蛸、枳实(枳壳)、木香、白术、白芍、陈皮(青皮)、鸡内金。结论:苦温入脾经药物为治疗胃溃疡的常用药,常用药物为甘草、白及、海螵鞘、延胡索、白芍、白术。
English Summary:
      To explore the rules and characteristics of herbs and their nature, flavor and meridian entry in treating gastric ulcer and to provide reference for Traditional Chinese Medicine(TCM) clinical treatment. Methods:1)To extract 220 papers from CNKI and select 107 papers which meet the inclusion criteria. Then summarize and analyze the nature, flavor, and meridian entry of the herbs used. 2)Analyze 2324 subject items by WTM database. Results:1)The top ten frequently used drugs in tumor-fever disease are: Baiji(Bletillae rhizoma), Gancao(Glycyrrhizae radix et rhizoma), Sanqi(Notoginseng radix et rhizoma), Haipiaoxiao(Sepiae endoconcha), Huangqi(Astragali radix), Baishao(Paeoniae radix alba), Huanlian(Coptidis rhizome), Yanhusuo(Corydalis rhizoma), Baizhu(Atractylodis macrocephalae rhizoma), Shengjiang(Ringiberis rhizoma recens)[Ganjiang(Zingiberis rhizoma), Jiangtan(Zingiberis rhizome praeparatum)]. Among these drugs, most of them can tonify body, clear heat, regulate qi and regulate blood. Mainly, the nature is warm, cold and the flavor is mostly bitter, and then sweet and pungent. Meridian entry is mostly spleen, and then stomach, liver and lung meridian. 2)Statistical analysis of WTM patents shows that top 10 herbs are: Gancao(Glycyrrhizae radix et rhizoma), Yanhusuo(Corydalis rhizoma), Baiji(Bletillae rhizoma), Haipiaoxiao(Sepiae endoconcha), Zhike(Aurantii fructus), Muxiang(Aucklandiae radix), Baizhu(Atractylodis macrocephalae rhizoma), Baishao(Paeoniae radix alba), Chenpi(Citri reticulatae pericarpium), Jineijin(Galli gigerii endothelium corneum). Conclusion:Based on the analysis of the nature, flavor and meridian entry, it could be found that bitter warm cold herbs which belong to spleen meridian entry were mostly common used in treating gastric ulcer. Commonly used drugs were Gancao(Glycyrrhizae radix et rhizoma), Baiji(Bletillae rhizoma), Haipiaoxiao(Sepiae endoconcha), Yanhusuo(Corydalis rhizoma), Baishao(Paeoniae radix alba), and Baizhu(Atractylodis macrocephalae rhizoma).
查看全文  查看/发表评论  下载PDF阅读器