To trace the original concept of Lijie and its cognitive mechanism.Methods:mental space mapping and conceptual blending process related to Lijie disease were analyzed by conceptual blending theory of cognitive linguistics.Results:Based on the similarities between characteristics of migratory arthralgia and joint deformity of Lijie disease and nature of wind and bamboo joint, ancient physicians mutually integrated the nature with human with certain relations and connections and Lijie concept were accomplished in the blending space.Conclusion:Through the mapping and orderly blending process between two input spaces of the nature and the human, most diseases of traditional Chinese medicine were named in the blending space according to its clinical manifestations.