To investigate the influence of integrated traditional Chinese and western medicine in the inflammation factors of patients with initial obesity type 2 diabetes. Methods:Initial obesity type 2 diabetes of 56 cases were randomly divided into the control group and experimental group. There were 28 patients in each group. The control group received regular treatment while the experimental group were given regular treatment combined with traditional Chinese medicine. After three months’ treatment, the curative effect was compared between the two groups. Results:After the treatment, the blood glucose level, C peptide release test results and inflammatory factor of the experimental group were better than that of the control group (P<0.05). Conclusion:Integrated traditional Chinese and western medicine treatment has a significant effect in improving the serum level of inflammatory factor in patients with initial obesity type 2 diabetes.