| 引用本文:朱广伟，李西文，陈士林.白芍饮片标准汤剂质量标准研究[J].世界中医药,2016,(05):. |
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| 白芍饮片标准汤剂质量标准研究 |
| Quality standard research on standard decoction of paeonialactiflora |
| 投稿时间：2016-04-12 |
| DOI：10.3969/j.issn.1673-7202.2016.05.001 |
| 中文关键词: 白芍 饮片 标准汤剂 指纹图谱 |
| English Keywords:Paeonia lactiflora Medicinal slices Standard decoction Fingerprint |
| 基金项目:中国中医科学院综合性大平台项目（编号：Z2014003-05） |
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| 中文摘要: |
| 目的：制备白芍饮片标准汤剂，并进行质量标准研究。方法：以水为溶剂，以标准化工艺制备标准汤剂，采用UPLC-DAD法测定芍药苷含量，并进行转移率、出膏率计算及指纹图谱研究。结果：10批次白芍样品制成的标准汤剂中芍药苷含量为1.69~2.60 mg/mL，转移率为60.47%~85.16%，平均转移率为71.62%，标准偏差为8.74%。出膏率范围为19.00%~26.50%，平均出膏率为21.89%，标准偏差为2.51%。指纹图谱共有峰11个，确认5个，分别是：氧化芍药苷、儿茶素、芍药内酯苷、芍药苷、苯甲酰芍药苷。结论：本方法处理样品简单，重复性好，可用于白芍标准汤剂的制备及质量标准研究。 |
| English Summary: |
| To study the preparation and quality standard of the standard decoction of paeonia lactiflora.Methods:The standard decoction of paeonia lactiflora was preparated with water by using standardization method and the content of peoniflorin was determined by UPLC-DAD.Then calculate the transfer rate,the rate of extractum and carry on the research of fingerprint.Results:The content of paeoniflo-rin in 10 batches of standard decoction of paeonia lactiflora is 1.69~2.60 mg/mL，the transfer rate is 60.47%~85.16%，the average transfer rate is 71.62% and the standard deviation is 8.74%.The rate of extractum is 19.00%~26.50%，the average yield is 21.89% and the standard deviation is 2.51%.There were 11common peaks，5 of which were identified，including oxypaeoniflorin，catechins,albiflorin，paeoniflorin and benzoylpaeoniflorin.Conclusion:The method is simple with good repeatability，and it can be used to study the preparation of the standard decoction of paeonia lacti-flora. |
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