To observe the clinical effects of Blood-activating and collaterals-dredging Formula on the treatment of unstable angina pectoris (UAP),and its impacts on high sensitive C-reactive protein (hs-CRP) and lipoprotein-associated phospholipase A2(Lp-PLA2).Methods:A total of 52 patients with UAP were randomly divided into control group (26 cases) and study group (26 cases).The control group received conventional treatment; the study group was treated with Blood-activating and collaterals-dredging Formula additionally on the basis of the control group.Both were treated for 8 weeks.The clinical symptoms and cardiographs were observed,the contents of Lp-PLA2 and high sensitive C-reactive protein (hs-CRP) in serum were determined before and after treatment.Results:The clinical efficiency of angina pectoris and cardiograph was 92.3% and 84.6%,respectively in study group,both were higher than the control group (73.1% and 61.5%,respectively) (P<0.05); the contents of Lp-PLA2 and CRP decreased greatly (P<0.05),and there were significant differences between two groups (P<0.05).Conclusion:Blood-activating and collaterals-dredging Formula is suitable for treating UAP,partly because of its function of lowering the contents of Lp-PLA2 and hs-CRP,as well as alleviating inflammation.