世界中医药

目的：研究膝关节骨性关节炎治疗采用风湿祛痛胶囊联合关节内注射透明质酸钠的临床效果。方法：收集我院门诊确诊为膝关节骨性关节炎（KOA）患者120例，随机分为2组：观察组为口服风湿祛痛胶囊联合每周关节内注射透明质酸钠2 mL,5周为1个疗程；对照组患者进行为每周关节内注射透明质酸钠2 mL,5周为1个疗程。每组患者60例，对比2组治疗效果。结果：观察组患者经过治疗后临床有效率为93.3%，显著高于对照组83.3%(P<0.05)。2组WOMAC和VAS评分，与治疗前比较均，有了显著性下降，差异有统计学意义(P<0.01)，观察组患者下降程度更明显，差异有统计学意义(P<0.05）。结论：使用风湿祛痛胶囊联合关节内注射玻璃酸钠治疗膝关节骨性关节炎疗效明确,值得在临床中推广应用。

English Summary:

To observe the clinical efficacy of Wind-damp-dispelling and pain-relieving Capsule with Sodium Hyaluronate in the treatment of knee osteoarthritis.Methods:In out-patient of our hospital,120 cases diagnosed with knee osteoarthritis were randomly divided into 2 groups.Treatment Group was treated with Wind-damp-dispelling and pain-relieving Capsule and a weekly injection of 2 ml Sodium Hyaluronate into knee joint cavity and the Control Group was treated with a weekly injection of 2 ml Sodium Hyaluronate into knee joint cavity.The treatment course was 5 weeks.The total effective rate,visual analogue scales (VAS),Western Ontario and McMaster University Osteoarthritis Index (WOMAC) were compared in 2 groups after treatment.Results:In Treatment Group,the total effective rate was 93.3%,and 83.3% in Control Group,the 2 groups showed significant difference (P<0.05).WOMAC and VAS scores of two groups of patients declined significantly after the treatment (P<0.05),WOMAC and VAS scores of two groups declined significantly after the treatment (P<0.01) and the Treatment Group had significantly better results than the Control Group (P<0.05).Conclusion:Wind-damp-dispelling and pain-relieving Capsule with Sodium Hyaluronate has higher clinical practical value in treatment of knee osteoarthritis and worthy to be promoted in clinical application.

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