世界中医药

作者	单位
利玲1，戴晓彬2	1 鄂东医疗集团黄石市中心医院药学部,黄石,435000 2 鄂东医疗集团黄石市中医医院(湖北理工学院附属医院)内科,黄石,435000

摘要点击次数: 1116

全文下载次数: 1090

中文摘要:

目的:探讨芪苈强心胶囊对慢性心力衰竭患者血浆脑钠肽(BNP)及肌钙蛋白(hs-cTnT)的影响。方法:选取2015年3月至2015年11月在鄂东医疗集团黄石市中心医院接受的慢性心力衰竭的60例患者,按随机数表法随机分为对照组和观察组,每组30例。观察组采用在常规方式前提下加服芪苈强心胶囊进用常规行治疗;对照组采用常规方式进行治疗。对比分析2组患者在治疗前后血浆BNP、hs-cTnT、hs-CRP、IL-1、IL-6、TNF-α水平、6 min的步行试验距离及心脏相关彩超指标以及临床总有效率。结果:2组患者与治疗前比较血浆BNP及hs-cTnT水平均有所下降,但观察组明显优于对照组,差异有统计学意义(P<0.05);2组患者与治疗前比较,在接受治疗之后6 min的步行试验距离均有所增加,但观察组明显高于对照组且相关彩超指标明显优于优于对照组,差异有统计学意义(P<0.05);2组患者与治疗前比较,接受治疗之后hs-CRP、IL-1、IL-6及TNF-α水平均有所下降,但观察组明显低于对照组,差异有统计学意义(P<0.05);观察组患者总有效率(93.33%)明显高于对照组(76.67%),2组数据对比,差异有统计学意义(P<0.05)。结论:芪苈强心胶囊可以有效地使患者心功能得到改善,能够使患者的血浆BNP及hs-cTnT水平显著降低,其有助于慢性心力衰竭进行治疗,值得在临床上推广及应用。

English Summary:

To investigate the effect of BNP and hs-cTnT of Qiliqiangxin capsule on patients with chronic heart.Methods:Select March 2015-November 2015 our hospital for 60 patients with chronic heart failure according to the random number table method were divided into control group and observation group.Observation group had 30 patients,in the conventional manner using the premise plus service Qiliqiangxin capsule treatment; control group of 30 patients were treated in a conventional manner.Analyzing of two groups of patients before and after treatment of levels of plasma BNP,hs-cTnT,hs-CRP,IL-1,IL-6,TNF-α,6-minute walk distance and cardiac ultrasound indicators and related clinical total efficiency.Results:Two groups of patients compared plasma BNP and hs-cTnT levels before treatment were decreased,but the observation group was gooder than the control group,being statistically significant (P<0.05); compared with the two groups of patients before treatment,receiving after treatment of 6-minute walk tested distance have increased,but the observation group was significantly higher and the relevant parameters were significantly better than the ultrasound than the control group being statistically significant(P<0.05);two groups of patients before treatment phase than,after receiving treatment hs-CRP,IL-1,IL-6 and TNF-α levels were decreased,but the observation group was significantly lower than the control group,being statistically significant (P<0.05);there is always a group of patients observed efficiency (93.33%) was significantly higher(76.67%),comparing two sets of data was statistically significant(P<0.05).Conclusion:Qiliqiangxin capsule can effectively improve patients′ heart function,enabling the plasma BNP and hs-cTnT levels were significantly reduced,which helps to treat chronic heart failure,worthy of promotion and application in clinical practice.

查看全文查看/发表评论下载PDF阅读器