世界中医药
文章摘要
引用本文:杜丽坤1,许志妍2,王冰梅1,徐洪涛1.贝牡莪消丸治疗结节性甲状腺肿的临床疗效观察[J].世界中医药,2016,(07):.  
贝牡莪消丸治疗结节性甲状腺肿的临床疗效观察
Observation on the Clinical Efficacy of Beimu Exiao Pills in Treating Nodular Goiter
投稿时间:2015-08-25  
DOI:10.3969/j.issn.1673-7202.2016.07.026
中文关键词:  结节性甲状腺肿  贝牡莪消丸  血瘀痰凝
English Keywords:Nodular goiter  Beimu Exiao pills  Blood stasis and phlegm stagnation type
基金项目:黑龙江省自然科学基金项目(编号:H201484);黑龙江省博士后科研启动资助项目(编号:LBH-Q13164)
作者单位
杜丽坤1,许志妍2,王冰梅1,徐洪涛1 1 黑龙江中医药大学附属第一医院哈尔滨150040 2 黑龙江中医药大学哈尔滨150040 
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中文摘要:
      目的:观察贝牡莪消丸对血瘀痰凝型结节性甲状腺肿的中医临床疗效。方法:将符合纳入标准的60例患者随机分为中药组及优甲乐组。2组分别服用中药制剂贝牡莪消丸及优甲乐,疗程12周。期间观察2组治疗前后的中医症状积分,比较中医临床疗效。结果:2组患者的中医症状积分均有下降,中药组优于优甲乐组(P<0.05);中药组中医临床疗效优于优甲乐组(P<0.05);2组均未出现不良反应,优甲乐组TSH水平较治疗前明显降低(P<0.05),而中药组较治疗前无统计学意义(P>0.05)。结论:贝牡莪消丸可明显降低血瘀痰凝型结节性甲状腺肿患者的中医症状积分,改善中医临床症状,具有较好的中医临床疗效及安全性。
English Summary:
      To observe the clinical efficacy of Beimu Exiao pills in treating Nodular Goiter(NG) of blood stasis and phlegm stagnation type. Methods: A total of 60 patients were randomly divided into traditional Chinese medicine group (taking Beimu Xiaoer pills) and euthyrox group (taking euthyrox). Treatment course lasts for 12 weeks. Record TCM symptom scores before and after treatment of the two groups, then compared the clinical efficacy of the two medication. Results: After treatment, patients in both groups showed lower TCM scores, while TCM group performed better than euthyrox group(P<0.05). Besides, the clinical efficacy of traditional Chinese medicine TCM group was higher than euthyrox group (P<0.05). There are no adverse reactions in both groups, however, TSH levels in euthyrox group is lower than before(P<0.05) while no significant difference showed in treatment group(P>0.05). Conclusion: Beimu Exiao pills can significantly reduce TCM scores in NG patients of blood stasis and phlegm stagnation type. Besides, it can relieve TCM symptoms and has good clinical efficacy and safety.
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