To evaluate the efficacy of Gubenfangxiao decoction(GBFXD)combined withDingchuanfutie Paste(DCFTP)on remission stage of asthmatic children who have syndrome of lung-spleen qi deficiency.Methods:A central randomized，parallel controlled，4-center clinical study was carried out on 263 cases of asthmatic children of remission stage.There were 132 cases in test group and 131 cases in control group.Children were orally administered GBFXD combined with DCFTP in the test group and inhaled Pulmicort Turbuhaler in the control group，and the treating period was 12 months.Results:1）Main outcome indicators evaluation:Compared to baseline，the frequency of asthma attack and respiratory infection were significantly reduced after 6 months of treatment and 12 months of treatment（P<0.01）.What is more，after 12 months，the frequency of respiratory infection in test group was notably lower than control group（P<0.05）.2）TCM syndrome outcome indicators evaluation:Compared to baseline，the TCM syndrome outcome indicators were all effectively improved no matter in test group or control group after 12 months.However the indicators of itchy nose and sneezing，running nose，cough，sweatiness，stool，and tongue manifestation were markedly improved than control group（P<0.01，P<0.05）.The total syndrome therapeutic effective rate was 93.08% in test group，82.31% in control group.The advantage of test group is remarkable（P<0.05）.Conclusion:The treatment of oral administration GBFXD combined with DCFTP on remission stage of asthmatic childrenwas safe and effective.