世界中医药

作者	单位
沈存思1，尹庆锋2，王蔚1，徐建亚1，谢彤1，汪受传1，单进军1	1 南京中医药大学中医儿科学研究所江苏省儿童呼吸疾病（中医药）重点实验室，南京，210023； 2 江苏法迈生医学科技有限公司，南京，210008

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中文摘要:

目的：对比研究6种临床常用于治疗感冒的中药口服液的抗炎、镇痛、解热作用。方法：通过二甲苯致小鼠耳廓肿胀实验考察其抗炎作用差异。采用冰醋酸致小鼠扭体实验考察其镇痛作用差异。采用干酵母致大鼠发热模型考察其解热作用差异。结果：各组中药口服液均可对抗二甲苯所致的炎性反应（P<0.05，P<0.01），蒲地蓝组、蓝芩组、胆木组及双黄连组要稍优于柴桂组及银黄组；各组中药口服液均能对抗乙酸所致小鼠的疼痛性反应（P<0.05，P<0.01），蓝芩组、双黄连组、胆木组要稍优于蒲地蓝组、银黄组及柴桂组；各组中药口服液均可降低干酵母所致大鼠升高的体温（P<0.05，P<0.01），柴桂组、双黄连组、胆木组及蒲地蓝组要稍优于蓝芩组、银黄组；结论：6种中药口服液均有抗炎、镇痛、解热作用，但其作用程度存在差异。

English Summary:

To evaluate six kinds of Chinese medicinal oral liquid on anti-inflammatory，analgesic and antipyretic effect on clinical treatment of catching cold.Methods:The anti-inflammatory effect was assessed by xylene-induced ear edema tests in mice.The analgesic effect was verified by HAc-induced writhing response in mice.The antipyretic action was monitored by dried yeast-induced pyrexia.Results:In all groups，Chinese medicinal oral liquid showed improved inflammatory response induced by HAc（P<0.05，P<0.01），while the efficacy of Pudilan group，Lanqin group，Danmu group and Shuanghuanglian group were slightly better than Chaigui group and Yinghuang group.All kinds of Chinese medicinal oral liquid ease the pain induced by HAc（P<0.05，P<0.01），while Lanqin group，Danmu group and Shuanghuanglian group were slightly better than Pudilan，Yinghuang group and Chaigui group.The fever induced by dried yeast was reduced by all kinds of Chinese material oral liquid，wihle Chaigui group，Shuanghuanglian group，Danmu group and Pudilan group were slightly better than Lanqin group and Yinghuang group.Conclusion:All six kinds of Chinese medicinal oral liquid had anti-inflammatory，analgesic and antipyretic efficacy，but slight differences on anti-inflammatory，analgesic and antipyretic effect between them existed.

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