| 引用本文:张海燕1，陈立宇2.不同剂量生大黄治疗重症急性胰腺炎62例分析[J].世界中医药,2016,(09):. |
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| 不同剂量生大黄治疗重症急性胰腺炎62例分析 |
| Analysis of Different Doses of Rhubarb in Treating 62 Cases of Severe Acute Pancreatitis |
| 投稿时间：2015-07-23 |
| DOI：10.3969/j.issn.1673-7202.2016.09.018 |
| 中文关键词: 不同剂量 生大黄 重症急性胰腺炎 分析 |
| English Keywords:Different dosage Rhubarb Severe acute pancreatitis Analysis |
| 基金项目:四川省卫生厅科研课题（编号：120206）；凉山州科技局项目课题（编号：14YYJS0018） |
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| 中文摘要: |
| 目的：研究分析不同剂量的生大黄治疗62例重症急性胰腺炎患者的效果。方法：从2013年6月至2014年6月，选择我院62例重症急性胰腺炎患者作为研究对象。以数字法随机将其分为观察组以及对照组，每组31例。对观察组使用大剂量生大黄进行治疗，对对照组使用小剂量生大黄进行治疗。对比观察2组的治疗效果。结果：2组治疗过程中，观察组出现出血1例，总发生例数为1例，较之对照组水肿4例，出血2例，坏死3例，总发生9例，明显更少，差异均有统计学意义（均P<0.05）。2组使用不同药物治疗后，观察组疗效为优者占67.74%（21/31），优良率达到96.77%（30/31），明显优于对照组的35.48%（11/31）、70.97%（22/31），差异均有统计学意义（均P<0.05）。2组患者经过治疗之后，对于自身症状改善情况评分比较均得到改善，但是观察组由（63.2±11.4）分改善至（87.3±10.3）分，改善程度明显高于对照组，差异具有统计学意义（P<0.05）。2组患者经过治疗后，Ranson以及APACHEII评分均得到改善，差异无统计学意义（P>0.05）。结论：大剂量的生大黄对SAP患者进行治疗时，对于缓解腹胀以及腹痛方面的效果好。 |
| English Summary: |
| To study the effect of rhubarb with different dosage in treating 62 cases of severe acute pancreatitis.Methods:Sixty-two cases of severe acute pancreatitis were selected as the research object from June 2013 to June 2014 and randomly divided into observation group and control group with 31 cases in each group.The observation group was treated with a large dose of rhubarb，and the control group was treated with a small dose of rhubarb.The effect of the treatment was compared between the two groups.Results:In the treatment group，bleeding occurred in 1 case，while 4 cases had edema，2 cases of bleeding and necrosis in 3 cases in the control group.The difference between the two group was statistically significant(P<0.05).After applying different doses in the two groups，the observation group’s remarkably curative effect rate was 67.74%(21 / 31)and the effective curative rate reached 96.77%(30/31)，which were significantly better than those of the control group(35.48% ［11/31］，70.97% ［22/31］.The difference between the two groups showed statistically significant(P<0.05).Symptoms score of patients in both the groups after treatment improved，but the observation group improved from(63.2±11.4)to(87.3±10.3)，significantly higher than that of the control group，showing statistically significant difference(P<0.05).Ranson and APACHEII score of patients in the two groups after treatment were improved but there was no significant difference(P>0.05).Conclusion:The large dose of Rhubarb for the treatment of SAP patients has good effect on the relief of abdominal distension and abdominal pain. |
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