世界中医药

目的:探讨通腑开窍汤对脑梗死急性期昏迷患者影响性,以期提高疗效。方法:选取2009年5月至2014年5月46例脑梗死急性期昏迷患者为研究对象,分为2组,对照组23例,常规西医治疗；观察组23例,加用通腑开窍汤治疗,观察治疗后在清醒时间和相关指标变化情况。结果:对照组治愈率21.74%、总有效率82.61%,观察组治愈率43.48%、总有效率95.65%,2组比较差异有统计学意义(P<0.05);对照组治疗后平均清醒时间为(6.23±1.13)d,观察组平均清醒时间为(4.11±0.88)d,观察组明显短于对照组,2组比较差异有统计学意义(P<0.05);2组治疗后在GCS评分、ADL评分、t-PA上较治疗前比较显著升高,NIHSS评分、PAI较治疗前比较显著下降,治疗前后2组内比较差异有统计学意义(P<0.05),观察组治疗后GCS评分、ADL评分、t-PA较对照组治疗后升高更明显,NIHSS评分、PAI下降下降更明显,2组治疗后比较差异有统计学意义(P<0.05)。结论:通腑开窍汤能缩短脑梗死急性期昏迷时间,提高疗效。

English Summary:

To investigate the effect of Bowels Relaxing and Orifice Opening Decoction on patients with acute cerebral infarction with coma in order to improve the clinical outcome.Methods:Total 46 cases of acute cerebral infarction coma patients during May 2009 to May 2014 in this study were divided into two groups，the control group with 23 patients were given conventional western medicine treatment，the 23 cases in the observation group received Bowels Relaxing and Orifice Opening Decoction with western medicine.The sober duration and related indicators changes were observed before and after the treatment.Results:The total curative rate of control group was 21.74%，the total effective rate was 82.61%，while the total curative rate of observation group was 43.48%，the total effective rate was 95.65%，the differences were significant(P<0.05)； in the control group the average sober duration was(6.23±1.13)d，the observation group(4.11±0.88)d，significantly shorter than the control group(P<0.05)； after treatment，the GCS score，ADL score，t-PA of the two group significantly improved，and NIHSS score and PAI decreased significantly(P<0.05).After treatment，the GCS score，ADL score，t-PA of the observation group increased more significantly，NIHSS score，PAI decline decreased more significantly(P<0.05).Conclusion:Bowels Relaxing and Orifice Opening Decoction can shorten the duration of coma with acute cerebral infarction with better efficacy.

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