| 引用本文:王颖，谢培凤，关崧，赵翠芳.固肾合剂治疗气阴两虚络脉瘀结型糖尿病肾病临床观察[J].世界中医药,2016,(09):. |
|
| 固肾合剂治疗气阴两虚络脉瘀结型糖尿病肾病临床观察 |
| Clinical Observation of Gushen Agent in the Treatment of Diabetic Kidney Disease of Qi-Yin Deficiency and Collaterals Stasis |
| 投稿时间：2015-11-22 |
| DOI：10.3969/j.issn.1673-7202.2016.09.022 |
| 中文关键词: 糖尿病肾病 固肾合剂 尿微量白蛋白 |
| English Keywords:Diabetic nephropathy Gushen agent Microalbuminuria |
| 基金项目:北京中医药大学自主选题资助项目（编号：2014-JYBZZ-JS-062） |
|
| 摘要点击次数: 1163 |
| 全文下载次数: 1108 |
| 中文摘要: |
| 目的：探讨固肾合剂治疗气阴两虚脉络瘀结型糖尿病肾病的临床疗效。方法：选择符合纳入标准的糖尿病肾病患者117例，采用随机数字表法随机分为治疗组62例和对照组55例，均予常规基础治疗，治疗组同时加用固肾合剂，对照组同时服用安博维，治疗8周；比较2组中医临床症状、24 h尿微量白蛋白、24 h尿蛋白定量、空腹血糖（FPG）、餐后2 h血糖（2 hPG）等指标改善情况。结果：固肾合剂治疗组与安博维对照组比较，2组症状积分用药前后均无统计学意义（P>0.05）。糖尿病肾病肾功能评定，2组临床控制率分别为治疗组29.03%，对照组32.73%，2组疗效无统计学意义（P>0.05）。2组24 h尿微量白蛋白、24 h尿蛋白、空腹血糖、餐后2 h血糖用药前后水平比较，经统计学检验无统计学意义（P>0.05）。中医证候疗效评定，2组显效率治疗组为19.35%，对照组为21.82%，无统计学意义（P>0.05）。结论：固肾合剂在改善气阴两虚络脉瘀结型糖尿病肾病的临床症状、降低蛋白尿等方面与厄贝沙坦疗效相当。 |
| English Summary: |
| To explore the clinical curative effect of Gushen agent in the treatment of diabetic kidney disease of qi-yin deficiency and collaterals stasis pattern. Methods: The 117 patients with diabetic nephropathy who met selection criteria were included and were randomly divided into treatment group 62 cases and control group 55 cases by the random number table method. Both of the two groups received conventional treatment. Patients in the treatment group were additionally treated with Gushen agent at the same time and the control group at the same time for 8 weeks. TCM Clinical symptoms, 24 h urine trace albumin, 24 h urine protein quantitative, fasting plasma glucose (FPG), blood sugar 2 hours after meal (2 h PG) measures of the two groups were compared. Results: Symptoms integral of the two groups before and after medication showed no significant difference (P>0.05). Clinical control rates for renal function evaluation of patients with diabetic nephropathy of the two groups were respectively was 29.03% in the treatment group and 32.73% in the control group. Differences in curative effect of the two groups showed no statistical significance (P>0.05). 24 h urine trace albumin, 24 h urine protein, fasting blood sugar and 2 h postprandial blood sugar medicine level before and after the treatment of the two groups indicated no statistically significant difference (P>0.05). TCM Syndrome efficacy evaluation of the two groups showed the efficiency of the treatment group was 19.35% and that of the control group was 21.82% with no significant difference (P>0.05). Conclusion: Gushen agent has equal effect in relieving clinical symptoms and reducing proteinuria of diabetic nephropathy of qi-yin deficiency and collaterals stasis pattern. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
