世界中医药

目的:客观评价清咽滴丸治疗颈椎前路手术后咽痛的临床疗效,以分析清咽滴丸在颈椎术后咽痛并发症治疗上的优势。方法:将2012—2015年间在北京中医药大学附属东直门医院骨科行颈椎前路手术后出现咽痛症的40例(失访7例)患者随机分为2组,清咽滴丸组14例予以清咽滴丸含服,雾化吸入组予以爱全乐溶液(异丙托溴铵溶液)+氯化钠溶液雾化吸入。观察2组治疗前后咽痛VAS评分、咽痛症状及咽痛综合征状的改善情况。结果:2组治疗前后咽痛VAS评分、咽痛症状及咽痛综合征状的改善情况差异有统计学意义(P<0.05),用药第3天时,清咽滴丸组和雾化吸入组的愈显率分别为28.57%和26.31%,用药第1、5、7天时,滴丸组和雾化组间比较差异无统计学意义(P>0.05)。结论:1)清咽滴丸可有效地改善颈椎前路手术后咽痛并发症的临床症状;2)清咽滴丸治疗术后咽痛的疗效显著,比雾化吸入疗法起效更快;3)清咽滴丸含服与雾化吸入总体疗效相似。

English Summary:

Objectively evaluate the clinical effect of Qingyan drop pill in the treatment of sore throat after anterior cervical spine surgery in order to analyze the advantages of Qingyan drop pill in the treatment of complications afrer cervical spine surgery.Methods:There were 40 patients(7 patients lost to follow-up)of sore throat symptoms after anterior cervical spine surgery in Dongzhimen hospital affiliated to Beijing university of traditional Chinese medicine from 2012 to 2015.They were randomly divided into two groups,14 cases were given sublingual Qingyan drop pills,and the others were given atrovent(ipratropium bromide solution)aerosol inhalation.The improvement was showed by VAS scores of sore throat,the improvement of sore throat symptom and sore throat syndrome.Results:The two groups in VAS scores,the improvement of sore throat symptom and sore throat syndrome between pre-treatment and post-treatment were statistically significant(P<0.05).The cure-remarkable-effectiveness rate of Qingyan drop pill group and aerosol inhalation group were 28.57% and 26.31% after 3 days’ treatment,but there were no statistically significant between two groups(P>0.05)after 1、5、7days’ treatment.Conclusion:1)Qingyan drop pill can effectively improve sore throat symptom after anterior cervical spine surgery;2)The curative effect of Qingyan drop pill in the treatment of postoperative sore throat is distinct and work faster than aerosol inhalation therapy;3)The overall curative effect of Qingyan drop pill is similar to aerosol inhalation therapy.

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