Using the method of activating blood circulation and removing stasis in the treatment of rheumatoid arthritis, analyze the clinical laboratory indexes before and after treatment to observe the therapeutic effect of promoting blood circulation and removing blood stasis method on controlling disease activity and its intervention of RA lipid disorders.Methods:Thirty-four cases of patients with rheumatoid arthritis were treated with activating blood circulation and removing blood stasis method, monitoring the blood lipid related indicators and disease activity index in the 4 week, 8 weeks of treatment.Results:After 4 weeks of treatment, patients with RA disease activity related indicators have declined: TC, LDL-C index decreased, ApoA1 index increased, and all with statistical significance(P<0.05). After 8 weeks of treatment, RA disease activity related indicators have declined: TC, LDL-C index decreased, ApoA1 index increased; and all had statistical significance(P<0.05).Conclusion:The method of promoting blood circulation and removing blood stasis can control the disease activity of RA patients, and it can also interfere with the disorder of lipid metabolism in patients with RA, prevent the occurrence of atherosclerosis and reduce the incidence of cardiovascular and cerebrovascular disease in patients with RA.